Health Utilities and Disutilities Associated With Complications of Type 1 Diabetes: A Systematic Review and Recommendations for Health Economic Models

Abstract

Objectives: Health economic models for type 1 diabetes (T1D) typically require utilities or disutilities associated with diabetes-related complications. We conducted a systematic review of studies reporting utilities and disutilities associated with T1D-related complications and assessed their methodological quality to identify a set of preferred disutilities. Methods: We searched 6 databases from inception to 30 April 2024. Data were extracted on study design, participant characteristics, complications, utility measurement methods, and reported values. Study quality was assessed based on sample size, population representativeness, appropriateness of the value sets, and statistical methods. ..